Medicinal Properties of Herbal Combination and M. officinalis Phytochemistry, Anti -Allergic Effect, Extraction Techniques, Remedial Applications

Iqra, Abdelhakim Aouf

Department of Chemistry, University of Agriculture Faisalabad, Pakistan

Laboratory of Applied Microbiology, University of Ferhat Abbas, Sétif-1, Algeria.

Submitted: 19-08-2025; Accepted: 26-12-2025; Published: 31-12-2025

 

 

Abstract

An everlasting herb of the Lamiaceae family, lemon balm (Melissa officinalis) is well known for its soothing and medical qualities. The botanical features, phytochemical nature and pharmacological benefits of M. officinalis are carefully examined in this review, that focuses on significant bioactive ingredients such as flavonoids, phenolic acids (including rosmarinic and caffeic acids), essential oils (like the citral and citronellal) and triterpenoids. The efficiency of extraction, the preservation of bioactivity and the sustainability of acquiring these bioactive compounds have all been substantially improved due to advanced extraction techniques including ultrasound-assisted extraction (UAE), microwave-assisted extraction (MAE), pressurized liquid extraction (PLE), supercritical fluid extraction (SFE) and matrix solid-phase dispersion (MSPD). The anti-allergic abilities of a combined herbal preparation comprised of the bur-marigold (Bidens tripartita), calendula (Calendula officinalis) and hawthorn (Crataegus monogyna) are presented in this review. Traditionally, these plants were historically used to support the immune balance, sooth tissues that are inflammatory and lessen inflammation. All three herbs have large amounts of flavonoids, polyphenols, triterpenoids and antioxidants that assist in controlling allergic responses, based on phytochemical analysis. The combined use of the extract reduce inflammatory symptoms, and protect tissues from damage due to oxidation, according to the experimental study. These herbs can serve as an effective natural treatment to treat allergies because of their cooperative activity, so enhances their overall medicinal effect.

 

Keywords: Anti-allergy or antioxidant activity combined herbal extract, extraction technique, bioactive compound.

Full length article    *Corresponding Author, e-mail: iqrakhadim159@gmail.com, doi# 10.71111/Science today/6-25-3-3-st-6